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Synthesis and apoptosis inducing ability of new anilino substituted pyrimidine sulfonamides as potential anticancer agents

โœ Scribed by Ahmed Kamal; D. Dastagiri; M. Janaki Ramaiah; J. Surendranadha Reddy; E. Vijaya Bharathi; M. Kashi Reddy; M. Victor Prem Sagar; T. Lakshminarayan Reddy; S.N.C.V.L. Pushpavalli; Manika Pal-Bhadra


Book ID
113583152
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
724 KB
Volume
46
Category
Article
ISSN
0223-5234

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โœ Ahmed Kamal; J. Surendranadha Reddy; M. Janaki Ramaiah; E. Vijaya Bharathi; D. D ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 407 KB

A series of new anilino substituted pyrimidine linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates were prepared and evaluated for their anticancer activity. The effects of four promising PBD conjugates on cell cycle of cancerous cell line A375 were investigated. These compounds showed the cha