Synthesis and biological evaluation of a
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Ahmed Kamal; J. Surendranadha Reddy; M. Janaki Ramaiah; E. Vijaya Bharathi; D. D
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Article
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2010
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Elsevier Science
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English
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A series of new anilino substituted pyrimidine linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates were prepared and evaluated for their anticancer activity. The effects of four promising PBD conjugates on cell cycle of cancerous cell line A375 were investigated. These compounds showed the cha