Stereoselective synthesis of amino-subst
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Won Jun Choi; Hee Sung Ahn; Hea Ok Kim; Sanghee Kim; Moon Woo Chun; Lak Shin Jeo
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Article
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2002
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Elsevier Science
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French
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Novel amino-substituted apio nucleoside (2R,4R)-LJ-45 as a potential anti-HBV agent was stereoselectively synthesized from the known oxazolidine 1 through a distant neighboring group effect. It is believed that this synthetic method using a chiral template, (-)-L-serine methyl ester can be generally