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Synthesis and antileishmanial evaluation of 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-1H-pyrazole derivatives

✍ Scribed by Maurício S. dos Santos; Mariana L.V. Oliveira; Alice M.R. Bernardino; Rosa M. de Léo; Veronica F. Amaral; Flavia T. de Carvalho; Leonor L. Leon; Marilene M. Canto-Cavalheiro


Book ID
113496251
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
205 KB
Volume
21
Category
Article
ISSN
0960-894X

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Efficient synthesis of 3-(4,5-dihydro-1H
✍ Ulrike Hary; Ulrike Roettig; Michael Paal 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 64 KB

A simple method for the synthesis of various 3-(4,5-dihydro-1H-imidazole-2-yl)-1H-indoles is described. Treatment of different substituted indoles with 1-acetyl-imidazolidin-2-one in the presence of phosphorus oxychloride afforded after hydrolysis in ethanol the corresponding 3-(4,5-dihydro-1H-imida