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Synthesis and Biological Evaluation of New 2-(4,5-Dihydro-1 H -imidazol-2-yl)-3,4-dihydro-2 H -1,4-benzoxazine Derivatives

✍ Scribed by Touzeau, Frédérique; Arrault, Axelle; Guillaumet, Gérald; Scalbert, Elizabeth; Pfeiffer, Bruno; Rettori, Marie-Claire; Renard, Pierre; Mérour, Jean-Yves


Book ID
118049524
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
303 KB
Volume
46
Category
Article
ISSN
0022-2623

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Efficient synthesis of 3-(4,5-dihydro-1H
✍ Ulrike Hary; Ulrike Roettig; Michael Paal 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 64 KB

A simple method for the synthesis of various 3-(4,5-dihydro-1H-imidazole-2-yl)-1H-indoles is described. Treatment of different substituted indoles with 1-acetyl-imidazolidin-2-one in the presence of phosphorus oxychloride afforded after hydrolysis in ethanol the corresponding 3-(4,5-dihydro-1H-imida