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Synthesis and antifungal activity of (±)-1-(5-aryl-3-pyridin-2-yl-4,5-dihydro-pyrazol-1-yl)-2-imidazol-1-yl-ethanone derivatives

✍ Scribed by Maria Grazia Mamolo; Daniele Zampieri; Valeria Falagiani; Luciano Vio; Elena Banfi


Book ID
114019053
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
160 KB
Volume
58
Category
Article
ISSN
0014-827X

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The title compound, C 18 H 18 N 2 O, was prepared by the reaction of 3-phenyl-1-(p-tolyl)prop-2-en-1-one with hydrazine hydrate in acetic acid. The pyrazole ring is in an envelope conformation. The crystal packing is stabilized by van der Waals forces.