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Synthesis and Antibacterial Activity of New 7-Piperazinylquinolones Containing a Functionalized 2-(Furan-3-yl)ethyl Moiety.

โœ Scribed by Alireza Foroumadi; Negar Mohammadhosseini; Saeed Emami; Bahram Letafat; Mohammad Ali Faramarzi; Nasrin Samadi; Abbas Shafiee


Publisher
John Wiley and Sons
Year
2007
Weight
21 KB
Volume
38
Category
Article
ISSN
0931-7597

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The synthesis of a new series of 1 beta-methylcarbapenems having a 1,3-diazabicyclo[3.3.0]octane-2,4-dione moiety is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bateria are determined and the effect of substituent on the bicyclic ring as well as st