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ChemInform Abstract: Synthesis and Antibacterial Activities of New 1β-Methylcarbapenems Having a 1,3-Diazabicyclo[3.3.0]octan-2,4-dione Moiety.

✍ Scribed by K.-H. NAM; C.-H. OH; Y.-W. HAM; K.-S. LEE; J.-H. CHO

Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
29
Category
Article
ISSN
0931-7597

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Synthesis and Antibacterial Activities o
Synthesis and Antibacterial Activities of New 1β-Methylcarbapenems Having a 1,3-Diazabicyclo[3.3.0]octan-2,4-dione Moiety
✍ Ki-Hong Nam; Chang-Hyun Oh; Young-Wan Ham; Ki-Soo Lee; Jung-Hyuck Cho 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 359 KB 👁 1 views

The synthesis of a new series of 1 beta-methylcarbapenems having a 1,3-diazabicyclo[3.3.0]octane-2,4-dione moiety is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bateria are determined and the effect of substituent on the bicyclic ring as well as st