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Synthesis and Antibacterial Activity of New 1β-Methyl carbapenem Having a Thiazolo[3,2-a]benzimidazole Moiety

✍ Scribed by Chang-Hyun Oh; Young-Wan Ham; Soon-Yung Hong; Jung-Hyuck Cho

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
214 KB
Volume
328
Category
Article
ISSN
0365-6233

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Synthesis and Antibacterial Activities of New 1β-Methylcarbapenems Having a 1,3-Diazabicyclo[3.3.0]octan-2,4-dione Moiety
✍ Ki-Hong Nam; Chang-Hyun Oh; Young-Wan Ham; Ki-Soo Lee; Jung-Hyuck Cho 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 359 KB

The synthesis of a new series of 1 beta-methylcarbapenems having a 1,3-diazabicyclo[3.3.0]octane-2,4-dione moiety is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bateria are determined and the effect of substituent on the bicyclic ring as well as st