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Syntheses of Optically Active α-Amino-acids from α-Keto-acids by Hydrogenolytic Asymmetric Transamination

✍ Scribed by HARADA, KAORU


Book ID
109653717
Publisher
Nature Publishing Group
Year
1966
Tongue
English
Weight
245 KB
Volume
212
Category
Article
ISSN
0028-0836

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Practical synthesis of optically active
✍ Joëlle Viret; Jacqueline Gabard; André Collet 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 290 KB

Simple amino acids (1) can be converted in fair to good yield into hydrazino acids (3) of like configuration by using KOCI instead of NaOCl to promote the Shestakov rearrangement of the intermediate hydantoic acids (2). It was shown fifteen years ago by Karady et al.,' and later by Custafsson,' that