6-Fluoroshikimates have interesting antibiotic properties. The enzymatic preparation of (6R)-and (6S)-fluoroshikimates from 3-fluorophosphoenolpyruvate is described. The multistep enzymatic conversion is followed by UV and 19F NMR spectroscopy. The shikimic acid pathway is an established target for
β¦ LIBER β¦
Syntheses of (6S)-6-fluoro- and (6R)-6-hydroxyshikimic acids
β Scribed by Chuanjun Song; Shende Jiang; Gurdial Singh
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 66 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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