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Convenient Syntheses of 2-, 5- and 6-Fluoro- and 2,6-Difluoro-L-DOPA.

โœ Scribed by Wei-Ping Deng; Kelli A. Wong; Kenneth L. Kirk

Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
33
Category
Article
ISSN
0931-7597

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๐Ÿ“œ SIMILAR VOLUMES

Trifluoromethanesulfonic acid, an altern
Trifluoromethanesulfonic acid, an alternative solvent medium for the direct electrophilic fluorination of DOPA: new syntheses of 6-[18F]fluoro-L-DOPA and 6-[18F]fluoro-D-DOPA
โœ Babak Behnam Azad; Raman Chirakal; Gary J. Schrobilgen ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 133 KB ๐Ÿ‘ 1 views

Previous work from this laboratory has shown that the direct fluorination of 3, 4-dihydroxy-phenyl-lalanine (l-DOPA) in anhydrous HF (aHF) or BF 3 /HF with F 2 is an efficient method for the synthesis of 6-fluoro-l-DOPA. Since then, 18 F-labeled 6-fluoro-l-DOPA ([ 18 F]6-fluoro-l-DOPA) has been used