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Syntheses of 4,5-Disubstituted Oxazoles via Regioselective C-4 Bromination

✍ Scribed by Li, Bryan; Buzon, Richard A.; Zhang, Zhijun


Book ID
125999902
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
102 KB
Volume
11
Category
Article
ISSN
1083-6160

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Synthesis of 2,4- and 2,5-Disubstituted
✍ Carla M. Counceller; Chad C. Eichman; Nicolas Proust; James P. Stambuli 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB 👁 1 views

## Abstract The rapid synthesis of 2,4‐ and 2,5‐disubstituted oxazoles __via__ metal‐catalyzed cross‐coupling reactions is reported. The 4‐ or 5‐position of the corresponding 4‐ or 5‐halogenated 2‐butylthiooxazoles was successfully functionalized __via__ Suzuki–Miyaura, Sonogashira and Stille cross