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ChemInform Abstract: Syntheses of 4,5-Disubstituted Oxazoles via Regioselective C-4 Bromination.

✍ Scribed by Bryan Li; Richard A. Buzon; Zhijun Zhang

Publisher: John Wiley and Sons
Year: 2008
Weight: 32 KB
Volume: 39
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200816133

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## Abstract The rapid synthesis of 2,4‐ and 2,5‐disubstituted oxazoles __via__ metal‐catalyzed cross‐coupling reactions is reported. The 4‐ or 5‐position of the corresponding 4‐ or 5‐halogenated 2‐butylthiooxazoles was successfully functionalized __via__ Suzuki–Miyaura, Sonogashira and Stille cross