MEVALONOLACTONE (14c,5) e t ( RS) MEVALONOLACTONE ( I 4 c -5 ) . Bernard ROUSSEAU, Jean-Pierre BEAUCOURT, Louis PICHAT\* S e r v i c e des Molecules Marquees -CEN-SACLAY -F. 91191 GIF-SUR-YVETTE Cedex Three new routes t 3 (RS) mvalonolactone s u i t a b l e for the double labeling w i t h i s o t
Syntheses de (R,S) mevalonolactones marquees au 14C ou au 13C : (R,S) mevalonolactone (14C-4,5) ; (14C-5) ; (14C-3′)
✍ Scribed by Bernard Rousseau; Jean-Pierre Beaucourt; Louis Pichat
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 213 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
## Two procedures are described f o r the two s t e p synthesis o f I 3f-14c_] mevalonolactone and H-methyl mevalonolactone from radioactive methyl magnesium iodide. The f i r s t route involves the addition of radiolabeled methyl mgnesiwn iodide with 1-12,4,10 t r i o x a adamantyl) 4 -t r i t y
LETOSTEINE, 2-[ l ( e t h o x y c a r b o n y l m e t h y l t h i o ) -e t h y l 1 4 -h y d r o x y c a r b o n y l t h i a z o l i d i n e i s l a b e l l e d w i t h e i t h e r carbon-14 o r S u l f u r -3 5 on t h e f o l l o w i n g p o s i t i o n s : t h e c a r b o x y l i c c a r b o n o f
## Abstract Carbonation with ^14^CO~2~ of penylethynyl‐lithium has given rise to (carboxyl‐^14^C) phenylpropiolic acid with 75 % yield based on ^14^CO^2^. The latter condensed with 2‐naphthol by treating with polyphosphoric acid afforded (4‐^14^C) β‐naphthoflavone, purified by silicagel low pressur
The carbonation with lPCO2 of the lithium derivative 6 prepared from p-chtorcdiphenytmethane 5 and n-but 1 lithium in THF i n presence of tetramethylmediamine gives (~4C-carbozyt) 2-I -chi!oro phenyll-2-phenylacetic acid 7 with 85 X yield based on d04. Action of thionyl chloride gave the correspond
## Abstract 9‐Hydroxy‐ellipticine (^14^C‐1), specific activity: 2,13 mCi/mM, has been synthesized for molecular biology and cancer research, from N‐methyl‐formanilide (^14^C‐formyl). The radioactive overall yield was 13,5% based on sodium formate ^14^C.