The ^14^C labelling of three compounds : HI‐6, TMB‐4 and pyrimidoxime is described from ^14^C‐formic acid, sodium salt. The compounds were prepared by lithiation and formylation with N‐methyl (^14^C)‐formanilide followed by introduction of the hydroxylamine moieties and alkylation of the pyridine. R
Synthese de l'hydroxy-9 ellipticine (14C-1) ou hydroxy-9 dimethyl-5, 11 (6h) pyrido [4,3-b] carbazole (14C-1)
✍ Scribed by Nguyen Van-Bac; Michel Herbert; Louis Pichat; Maurice-Marie Janot; Nguyen Dat-Xuong
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- French
- Weight
- 286 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
9‐Hydroxy‐ellipticine (^14^C‐1), specific activity: 2,13 mCi/mM, has been synthesized for molecular biology and cancer research, from N‐methyl‐formanilide (^14^C‐formyl). The radioactive overall yield was 13,5% based on sodium formate ^14^C.
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