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Synthese DU N- [(ethyl - 1 pyrrolidinyl -2) methyl] methoxy-2 sulfamoyl -5 benzamide (sulpiride) marque AU 14C

✍ Scribed by J. P. Noël; A. Benakis; M. Herbert; L. Pichat; M. Thominet

Publisher
John Wiley and Sons
Year
1972
Tongue
French
Weight
287 KB
Volume
8
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Sulpiride: N‐[léthyl‐l pyrrolidinyl‐2) methyl] methoxy‐2 sulfamoyl‐5 benzamide, has been labelled with carbon 14 in the carbonyl group by a five step synthesis from barium carbonate ^14^C. The specific activity of the final product is 37.6 mCi/mM (110 μCi/mg), and the radiochemical purity 99.5%. UV‐ and mass spectrometry confirm the identity of the labelled compound with the reference material, as well as the position labelled with ^14^C.

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