In the title molecule, C~21~H~26~O~2~, there are two C=C bonds [1.321 (4) and 1.334 (4) Å], which contribute to the planarity of ring __A__ along with the carbonyl group. Rings __B__ and __C__ have regular chair conformations, while ring __D__ has an envelope conformation. In the crystal structure,
Synthese des 4α et 4β-deuterio 3β, 17β-dihydroxy androsta-5-ene
✍ Scribed by Antoinette Viger; Suzy Coustal; Andrée Marquet
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 511 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0040-4020
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A stereoselective synthesis of the highly active aldosterone antagonist prorenone (7) is described. 6R,7&Methylensteroide sind pharmakologisch in der Gestagen-1) und Antialdosteronreihe2) von groBem Interesse. Bisher sind zwei Methoden bekannt, 6B,7B\_Methylensteroide darzustellen. Einetseits die Um