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Synthese Amelioree de la Progesterone 14C-4

✍ Scribed by H. Hoellinger; Nguyen-Hoang-Nam; L. Pichat

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
262 KB
Volume
10
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

La synthèse améliorée de la progestérone ^14^C‐4 est décrite. La purification de la progestérone ^14^C‐4 par chromatographie sur colonne de silicate de Mg et CCM préparative a permis l'isolement de deux sous‐produits: isoprogestérone ^14^C‐4 et trioxo‐3,5,20‐seco A‐4,5 pregnane ^14^C‐4, identifiés par spectrométrie RMN et de masse. Rendement radioactif global: 40% par rapport à ^14^CO~3~Ba, activité spécifique: 59 mCi/mM.

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