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Symptomatic Pulmonary Hypertension in a Child with Sickle Cell Disease

โœ Scribed by Karrie Villavicencio; Dunbar Ivy; Laura Cole; Rachelle Nuss

Book ID
113744557
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
166 KB
Volume
152
Category
Article
ISSN
1097-6833

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In patients with sickle cell disease, anemia is a recognized risk factor for stroke, death, and the development of pulmonary hypertension. We have proposed that hemolytic anemia results in endothelial dysfunction and vascular instability and can ultimately lead to a proliferative vasculopathy leadin