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Pulmonary hypertension in patients with sickle cell disease: a longitudinal study

✍ Scribed by Kenneth I. Ataga; Charity G. Moore; Susan Jones; Oludamilola Olajide; Dell Strayhorn; Alan Hinderliter; Eugene P. Orringer


Book ID
108673780
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
107 KB
Volume
134
Category
Article
ISSN
0007-1048

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In patients with sickle cell disease, anemia is a recognized risk factor for stroke, death, and the development of pulmonary hypertension. We have proposed that hemolytic anemia results in endothelial dysfunction and vascular instability and can ultimately lead to a proliferative vasculopathy leadin