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Pulmonary Hypertension in Children and Adolescents with Sickle Cell Disease

✍ Scribed by O. C. Onyekwere; A. Campbell; M. Teshome; S. Onyeagoro; C. Sylvan; A. Akintilo; S. Hutchinson; G. Ensing; P. Gaskin; G. Kato; S. Rana; J. Kwagyan; V. Gordeuk; J. Williams; O. Castro


Publisher
Springer
Year
2007
Tongue
English
Weight
132 KB
Volume
29
Category
Article
ISSN
0172-0643

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In patients with sickle cell disease, anemia is a recognized risk factor for stroke, death, and the development of pulmonary hypertension. We have proposed that hemolytic anemia results in endothelial dysfunction and vascular instability and can ultimately lead to a proliferative vasculopathy leadin