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Sickle cell disease, pulmonary hypertension, and sarcoidosis

✍ Scribed by Lorenz H. Lehmann; Hanno Riess; Isrid Sturm


Publisher
Springer
Year
2008
Tongue
English
Weight
100 KB
Volume
87
Category
Article
ISSN
0939-5555

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In patients with sickle cell disease, anemia is a recognized risk factor for stroke, death, and the development of pulmonary hypertension. We have proposed that hemolytic anemia results in endothelial dysfunction and vascular instability and can ultimately lead to a proliferative vasculopathy leadin