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Severe pulmonary hypertension in an adolescent with sickle cell disease

โœ Scribed by James G. Taylor VI; Gerald M. Woods; Roberto Machado; Gregory J. Kato; Mark T. Gladwin


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
174 KB
Volume
83
Category
Article
ISSN
0361-8609

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โœ Gregory J. Kato; Matthew Hsieh; Roberto Machado; James Taylor VI; Jane Little; J ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 191 KB ๐Ÿ‘ 1 views

In patients with sickle cell disease, anemia is a recognized risk factor for stroke, death, and the development of pulmonary hypertension. We have proposed that hemolytic anemia results in endothelial dysfunction and vascular instability and can ultimately lead to a proliferative vasculopathy leadin