Cardiopulmonary imaging, functional and laboratory studies in sickle cell disease associated pulmonary hypertension
β Scribed by Eduard J. van Beers; Erfan Nur; Cornelia M. Schaefer-Prokop; Melvin R. Mac Gillavry; Joost W.J. van Esser; Dees P.M. Brandjes; Maria C. Kappers-Klunne; Ashley J. Duits; Frits A.J. Muskiet; John-John B. Schnog; Bart J. Biemond
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 116 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In patients with sickle cell disease, anemia is a recognized risk factor for stroke, death, and the development of pulmonary hypertension. We have proposed that hemolytic anemia results in endothelial dysfunction and vascular instability and can ultimately lead to a proliferative vasculopathy leadin
## Abstract Pulmonary hypertension (PH), a risk factor for mortality in sickle cell disease (SCD), has pathologic features of both pulmonary arterial hypertension (PAH) and PH related to leftβsided heart disease (LHD) suggesting a link between these two entities. We hypothesized that both are chara