To determine the efficacy of adjuvant chemotherapy in patients with advanced head and neck squamous carcinoma, the National Cancer Insitute initiated a multi-institutional, prospective randomized trial termed the Head and Neck Contracts Program. Between 1978 and 1982,462 patients with resectable Sta
Symposium: Adjuvant cancer therapy of head and neck tumors. Predefinitive and postdefinitive chemotherapy for locally advanced squamous carcinoma of the head and neck
β Scribed by John M. Kirkwood; Daniel Miller; Ralph Weichselbaum; Susan W. Pitman
- Book ID
- 115040656
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 617 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0023-852X
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## Abstract ## Background. Induction chemotherapy may contribute to decreased local and distant recurrences in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN) resectable for cure. ## Methods. Patients with previously untreated locally advanced stage IIIβIV (N0
## Abstract Fiftyβone patients (32 previously untreated, 19 previously treated) with advanced squamous cell carcinoma of the head and neck received a single course of combination chemotherapy consisting of high dose __cis__βplatinum (DDP), bleomycin (Bleo), Β± high dose methotrexate (MTX). Thirtyβth