Sustained release emphasizing recombinant human bone morphogenetic protein-2
β Scribed by Shelley R Winn; Hasan Uludag; Jeffrey O Hollinger
- Book ID
- 114176521
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 331 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0169-409X
No coin nor oath required. For personal study only.
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## Abstract A bioactive and resorbable scaffold is necessary to exhibit the osteoinductive potency of recombinant human bone morphogenetic proteinβ2 (rhBMPβ2). In a previous study, we found that synthetic octacalcium phosphate (OCP) enhances bone regeneration and is replaced by newly formed bone af
The study reported describes a combination of recombinant human bone morphogenetic protein-2 (rhBMP-2) and collagen (C) to regenerate bone. Unilateral critical-sized defects (CSDs) were prepared in radii of 32 skeletally mature New Zealand white rabbits. Rabbits were divided evenly among four treatm