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Bone induction by Escherichia coli -derived recombinant human bone morphogenetic protein-2 compared with Chinese hamster ovary cell-derived recombinant human bone morphogenetic protein-2

✍ Scribed by K. Bessho; Y. Konishi; S. Kaihara; K. Fujimura; Y. Okubo; T. Iizuka


Book ID
117834663
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
406 KB
Volume
38
Category
Article
ISSN
0266-4356

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Recombinant human bone morphogenetic protein-2 (rhBMP-2) is known to induce orthotopic and ectopic bone formation in vivo. Several in vitro studies using rat or mouse clonal cell lines have shown that rhBMP-2 may be involved in the differentiation of osteoblasts from osteoblast precursor cells or st