Recombinant human bone morphogenetic protein-2 (rhBMP-2) is known to induce orthotopic and ectopic bone formation in vivo. Several in vitro studies using rat or mouse clonal cell lines have shown that rhBMP-2 may be involved in the differentiation of osteoblasts from osteoblast precursor cells or st
In vivo bone-forming capacity of human bone marrow-derived stromal cells is stimulated by recombinant human bone morphogenetic protein-2
β Scribed by Hiroshi Yamagiwa; Naoto Endo; Kunihiko Tokunaga; Tadashi Hayami; Hiroshi Hatano; Hideaki E. Takahashi
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 624 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0914-8779
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## Abstract Bone morphogenetic protein (BMP)β2 has a critical role in bone formation and regeneration. Therefore, the ability to immobilize this molecule in certain matrices may be crucial in bone tissue engineering. Using carbodiimide chemistry, BMPβ2 was directly immobilized on silk fibroin films