Aberrations in the function of alpha-catenin (alpha-cat), the anchoring protein of E-cadherin, are believed to cause dysfunction of the cadherin-catenin complex, leading to disturbed cell-cell adhesion. It has been suggested that expression of alpha-cat in human tumours might be a better indicator o
Survivin expression is a negative prognostic marker in laryngeal squamous cell carcinoma and is associated with p53 accumulation
✍ Scribed by J Pizem; A Cör; N Gale
- Book ID
- 108779716
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 294 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0309-0167
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were used as a control group. p53 overexpression indicating a mutated p53 gene was analyzed by immunohistochemistry using the mouse monoclonal antibody D0-7. ## RESULTS. Approximately 82% of carcinomas that recurred locally expressed p53 compared with only 29% of those with local control (P õ 0.0
## Background: Patients with superficial (mucosal or submucosal) esophageal carcinoma (sec) have significantly better survival rates than patients with advanced carcinoma. some patients with advanced esophageal carcinoma have been reported to test positive for serum p53 antibodies (abs). because ve
## Abstract Oral squamous cell carcinoma (OSCC) is a solid neoplasm exhibiting aggressive tumor phenotypes with unpredictable biological behavior. Recent studies suggested that high expression of the antiapoptotic protein survivin might be associated with adverse outcome in oral cancer patients. To