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Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities

โœ Scribed by Yamazaki, Hiroshi; Shimizu, Makiko


Book ID
120237408
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
533 KB
Volume
85
Category
Article
ISSN
0006-2952

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Hepatic flavin-containing monooxygenase (FMO) activity of microsomes from adult CD-1, Swiss-Webster, C57BL/6, and DBA/2 mice was found to be significantly higher in females than in males. Based on protein and mRNA levels in CD-1 mice, FMO forms responsible for the gender difference in FMO activity w