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In vitro and in vivo inhibition of human flavin-containing monooxygenase form 3 (FMO3) in the presence of dietary indoles

✍ Scribed by John R Cashman; Yeng Xiong; Jing Lin; Hans Verhagen; Geert van Poppel; Peter J van Bladeren; Shelley Larsen-Su; David E Williams


Book ID
113994502
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
342 KB
Volume
58
Category
Article
ISSN
0006-2952

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Gender differences in hepatic expression
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Hepatic flavin-containing monooxygenase (FMO) activity of microsomes from adult CD-1, Swiss-Webster, C57BL/6, and DBA/2 mice was found to be significantly higher in females than in males. Based on protein and mRNA levels in CD-1 mice, FMO forms responsible for the gender difference in FMO activity w