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Survey of the year 2004: literature on applications of isothermal titration calorimetry

✍ Scribed by Abdessamad Ababou; John E. Ladbury


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
243 KB
Volume
19
Category
Article
ISSN
0952-3499

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✦ Synopsis


Abstract

The market for commercially available isothermal titration calorimeters continues to grow as new applications and methodologies are developed. Concomitantly the number of users (and abusers) increases dramatically, resulting in a steady increase in the number of publications in which isothermal titration calorimetry (ITC) plays a role. In the present review, we will focus on areas where ITC is making a significant contribution and will highlight some interesting applications of the technique. This overview of papers published in 2004 also discusses current issues of interest in the development of ITC as a tool of choice in the determination of the thermodynamics of molecular recognition and interaction. Copyright Β© 2005 John Wiley & Sons, Ltd.


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✍ Adessamad Ababou; John E. Ladbury πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 241 KB

## Abstract Isothermal titration calorimetry (ITC) can provide a full thermodynamic characterization of an interaction. Its usage does not suffer from constraints of molecular size, shape or chemical constitution. Neither is there any need for chemical modification or attachment to solid support. T

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✍ Matthew J. Cliff; John E. Ladbury πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 125 KB

## Abstract Isothermal titration calorimetry (ITC) is becoming widely accepted as a key instrument in any laboratory in which quantification of biomolecular interactions is a requisite. The method has matured with respect to general acceptance and application development over recent years. The numb

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## Abstract Over the last decade isothermal titration calorimetry (ITC) has developed from a specialist method which was largely restricted in its use to dedicated experts, to a major, commercially available tool in the arsenal directed at understanding molecular interactions. The number of those p

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✍ Robert J. Falconer; Brett M. Collins πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 281 KB

Isothermal titration calorimetry (ITC) is now an established and invaluable method for determining the thermodynamic constants, association constant and stoichiometry of molecular interactions in aqueous solutions. The technique has become widely used by biochemists to study protein interaction with