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A survey of the year 2003 literature on applications of isothermal titration calorimetry

✍ Scribed by Matthew J. Cliff; Aldo Gutierrez; John E. Ladbury


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
186 KB
Volume
17
Category
Article
ISSN
0952-3499

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✦ Synopsis


Abstract

Over the last decade isothermal titration calorimetry (ITC) has developed from a specialist method which was largely restricted in its use to dedicated experts, to a major, commercially available tool in the arsenal directed at understanding molecular interactions. The number of those proficient in this field has multiplied dramatically, as has the range of experiments to which this method has been applied. This has led to an overwhelming amount of new data and novel applications to be assessed. With the increasing number of publications in this field comes a need to highlight works of interest and impact. In this overview of the literature we have attempted to draw attention to papers and issues for which both the experienced calorimetrist and the interested dilettante hopefully will share our enthusiasm. Copyright Β© 2004 John Wiley & Sons, Ltd.


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## Abstract The market for commercially available isothermal titration calorimeters continues to grow as new applications and methodologies are developed. Concomitantly the number of users (and abusers) increases dramatically, resulting in a steady increase in the number of publications in which is

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