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A survey of the year 2002 literature on applications of isothermal titration calorimetry

✍ Scribed by Matthew J. Cliff; John E. Ladbury

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
125 KB
Volume
16
Category
Article
ISSN
0952-3499

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✦ Synopsis

Abstract

Isothermal titration calorimetry (ITC) is becoming widely accepted as a key instrument in any laboratory in which quantification of biomolecular interactions is a requisite. The method has matured with respect to general acceptance and application development over recent years. The number of publications on ITC has grown exponentially over the last 10 years, reflecting the general utility of the method. Here all the published works of the year 2002 in this area have been surveyed. We review the broad range of systems to which ITC is being directed and classify these into general areas highlighting key publications of interest. This provides an overview of what can be achieved using this method and what developments are likely to occur in the near future. Copyright Β© 2003 John Wiley & Sons, Ltd.

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Survey of the year 2004: literature on a
Survey of the year 2004: literature on applications of isothermal titration calorimetry
✍ Abdessamad Ababou; John E. Ladbury πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 243 KB

## Abstract The market for commercially available isothermal titration calorimeters continues to grow as new applications and methodologies are developed. Concomitantly the number of users (and abusers) increases dramatically, resulting in a steady increase in the number of publications in which is

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✍ Adessamad Ababou; John E. Ladbury πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 241 KB

## Abstract Isothermal titration calorimetry (ITC) can provide a full thermodynamic characterization of an interaction. Its usage does not suffer from constraints of molecular size, shape or chemical constitution. Neither is there any need for chemical modification or attachment to solid support. T

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✍ Matthew J. Cliff; Aldo Gutierrez; John E. Ladbury πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 186 KB

## Abstract Over the last decade isothermal titration calorimetry (ITC) has developed from a specialist method which was largely restricted in its use to dedicated experts, to a major, commercially available tool in the arsenal directed at understanding molecular interactions. The number of those p

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✍ Robert J. Falconer; Brett M. Collins πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 281 KB

Isothermal titration calorimetry (ITC) is now an established and invaluable method for determining the thermodynamic constants, association constant and stoichiometry of molecular interactions in aqueous solutions. The technique has become widely used by biochemists to study protein interaction with

The characterization of a novel dendriti
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✍ Daniel J. Coles; Shu Yang; Rodney F. Minchin; Istvan Toth πŸ“‚ Article πŸ“… 2008 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 138 KB

## Abstract Understanding the nature of binding of polycationic dendrimers to DNA provides useful information on their role in gene delivery. In the present study, we have characterized the interaction of several peptide‐based polycationic dendrimers with salmon sperm DNA using isothermal titration