𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Suppression of proline-directed protein kinase FAexpression inhibits the growth of human chronic myeloid leukaemia cells

✍ Scribed by Hsu, C-P; Hsueh, S-F; Yang, C-C; Langrish, V

Book ID
119981026
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
197 KB
Volume
82
Category
Article
ISSN
0007-0920

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Suppression of proline-directed protein
Suppression of proline-directed protein kinase FA systemically inhibits the growth of human acute leukemia cells
✍ Chih-Ping Hsu; Chuan-Ching Yang; Shiaw-Der Yang πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 100 KB πŸ‘ 1 views

Initial studies revealed that proline-directed protein kinase F A (PDPK F A ) was overexpressed in various cancerous tissues relative to normal controls. However, the functional role of overexpressed PDPK F A in cancer remains to be established. In this report, we explore the potential role of PDPK

Suppression of proline-directed protein
Suppression of proline-directed protein kinase FA potentiates apoptotic induction and greatly enhances chemosensitivity in human acute lymphoblastic leukemia cells
✍ Chih-Ping Hsu; Chuan-Ching Yang; Sheng-Fen Hsueh M.S.; Chien-Chung Peng B.S.; Hs πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 125 KB πŸ‘ 1 views

## BACKGROUND. Previously, the authors reported that specific antisense suppression of overexpressed proline-directed protein kinase (PDPK) F A enhances the chemosensitivity of various clinical anticancer drugs up to ΟΎ 100-fold in human prostate carcinoma cells, suggesting an association of PDPK F

Protein kinase B modulates the sensitivi
Protein kinase B modulates the sensitivity of human neuroblastoma cells to insulin-like growth factor receptor inhibition
✍ Ana S. Guerreiro; Danielle Boller; Tarek Shalaby; Michael A. Grotzer; Alexandre πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 French βš– 710 KB

## Abstract The potential of the novel insulin‐like growth factor receptor (IGF‐IR) inhibitor NVP‐AEW541 as an antiproliferative agent in human neuroblastoma was investigated. Proliferation of a panel of neuroblastoma cell lines was inhibited by NVP‐AEW541 with IC~50~ values ranging from 0.15 to 5