Initial studies revealed that proline-directed protein kinase F A (PDPK F A ) was overexpressed in various cancerous tissues relative to normal controls. However, the functional role of overexpressed PDPK F A in cancer remains to be established. In this report, we explore the potential role of PDPK
β¦ LIBER β¦
Suppression of proline-directed protein kinase FA expression potentiates erythroid differentiation of human myeloid leukemia cells
β Scribed by Chih-Ping Hsu; Chuan-Ching Yang; Shiaw-Der Yang
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 167 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0008-543X
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## BACKGROUND. Previously, the authors reported that specific antisense suppression of overexpressed proline-directed protein kinase (PDPK) F A enhances the chemosensitivity of various clinical anticancer drugs up to ΟΎ 100-fold in human prostate carcinoma cells, suggesting an association of PDPK F