Notch signaling inhibits the growth of the human chronic myeloid leukemia cell line K562
β Scribed by Dan-Dan Yin; Feng-Yun Fan; Xing-Bin Hu; Li-Hong Hou; Xue-Ping Zhang; Li Liu; Ying-Min Liang; Hua Han
- Book ID
- 104040769
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 406 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0145-2126
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## Abstract The K562 cell line derived from a CML patient in blast crisis was examined for properties of B and T lymphocytes and cell lines. K562 lacks the B markers of immunoglobulin, EpsteinβBarr virus (EBV) genome and associated nuclear antigen, and receptors for EBV. A low proportion of cells f
## Abstract Arachidonic acid (AA)βinduced apoptotic death of K562 cells (human chronic myeloid leukemic cells) was characteristic of reactive oxygen species (ROS) generation and mitochondrial depolarization. __N__βAcetylcysteine pretreatment rescued viability of AAβtreated cells and abolished mitoc