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Suppression of H-ras-mediated transformation in NIH3T3 cells by a ras ribozyme

✍ Scribed by Tadao Funato; Toshiya Shitara; Takeshi Tone; Lu Jiao; Mohammed Kashani-Sabet; Kevin J. Scanlon

Book ID
115784171
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
571 KB
Volume
48
Category
Article
ISSN
0006-2952

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## Abstract Activating Ras mutations are involved in a significant fraction of human tumors. A suppressor screen using a retroviral mouse fibroblast cDNA library was performed to identify novel factors in Ras‐mediated transformation. We identified a novel potent inhibitor of Ras‐mediated morphologi