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Oncogenic Ras-mediated downregulation of Clast1/LR8 is involved in Ras-mediated neoplastic transformation and tumorigenesis in NIH3T3 cells

✍ Scribed by Sun-Hyo Ryu; Ki Hwan Kim; Hong-Beum Kim; Mi-Hwa Kim; Na-Hee Kim; Yoonsung Kang; Jin Won Hyun; Hong Joo Seo; Jae-Yeul Jun; Ho Jin You

Book ID: 108586785
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 395 KB
Volume: 101
Category: Article
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2010.01626.x

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## Abstract We have reported earlier the isolation of two recessive, serum‐ and anchoragedependent revertants (R116 and R260) from a c‐H‐ras oncogene‐transformed NIH 3T3 line. In both revertants, the oncogene was fully expressed and fusion of either revertant with (untransformed) NIH 3T3 cells, or