We examined the effects of the introduction of H-ras oncogene into murine cell line NIH3T3 on growth inhibition by topoisomerase-I (topo-I) inhibitors. The H-ras-transformed cells (pT22-3) showed approximately I 2-fold increased sensitivity to a novel topo-l inhibitor, NB-506 [6-N-formylamino-I2,I3d
Selective Cytotoxicity of Azatyrosinamides Against ras-Transformed NIH 3T3 Cells.
β Scribed by H. P. Wang; T. L. Hwang; On Lee; Y. J. Tseng; C. Y. Shu; S. J. Lee
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 20 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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