Suppression of allogeneic T cells proliferation by CD3/CD46-induced T-regulatory 1 cells
β Scribed by Dong Chen; Yan Zhang; Ming Li; Chi Zhang; Gang Chen; Zhishui Chen; Shi Chen; Weijie Zhang
- Book ID
- 107406096
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- Chinese
- Weight
- 352 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0510-9752
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Interleukinβ2 (ILβ2) treatment is currently used to enhance T cellβmediated immune responses against tumors or in viral infections. At the same time, ILβ2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that ILβ2 is a
## Abstract For Abstract see ChemInform Abstract in Full Text.
In the presence of interleukin 2 (IL2), soluble anti-CD3 monoclonal antibodies can stimulate highly purified normal T lymphocytes to proliferate. In these experiments HLADR' T cells constituted 13 to 20% of the total cell population, and other HLADR' cells, such as monocytes and B lymphocytes, const