𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells

✍ Scribed by Leonie S. Taams; Milica Vukmanovic-Stejic; Jay Smith; Padraic J. Dunne; Jean M. Fletcher; Fiona J. Plunkett; Saskia B. Ebeling; Giovanna Lombardi; Malcolm H. Rustin; Johannes W. J. Bijlsma; Floris P. J. G. Lafeber; Mike Salmon; Arne N. Akbar


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
289 KB
Volume
32
Category
Article
ISSN
0014-2980

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Inhibition of human T cell proliferation
✍ Claire N. Manzotti; Helen Tipping; Laura C. A. Perry; Karen I. Mead; Patrick J. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 263 KB 👁 2 views

CD28 and CTLA-4 are opposing regulators of T cell activation, triggered by the two ligands CD80 and CD86. How these ligands promote either T cell activation via CD28 or inhibition via CTLA-4 is not understood. Using CD80 and CD86 molecules expressed on transfected cells, we have identified a major d

CD4+CD25+ T cells as immunoregulatory T
✍ Jian-Guo Chai; Julia Y. S. Tsang; Robert Lechler; Elizabeth Simpson; Julian Dyso 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 482 KB 👁 1 views

We have further characterized the in vitro phenotype and function of anergic and suppressive CD4(+)25(+) T cells. Following TCR ligation, DO.11.10 CD4(+)25(+) T cells suppress the activation of OT-1 CD8(+)25(-) T cells in an antigen nonspecific manner. Although suppression was seen when using a mixt