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CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells

✍ Scribed by Lukas Cederbom; Håkan Hall; Fredrik Ivars


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
94 KB
Volume
30
Category
Article
ISSN
0014-2980

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✍ Rie Hakamada-Taguchi; Takuma Kato; Hiroshi Ushijima; Masaaki Murakami; Toshimits 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB

Co-stimulatory signals mediated by the interaction of B7-1/B7-2 with CD28 are important for the activation of CD4 + T cells stimulated with antigen on antigen-presenting cells. There are controversies about the expression and function of B7-1/B7-2 on CD4 + T cells. The aim of this study was to analy