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Superiority of high-dose over intermediate-dose cytosine arabinoside in the treatment of patients with high-risk acute myeloid leukemia: results of an age-adjusted prospective randomized comparison

✍ Scribed by Kern, W; Aul, C; Maschmeyer, G; Schönrock-Nabulsi, R; Ludwig, W D; Bartholomäus, A; Bettelheim, P; Wörmann, B; Büchner, T; Hiddemann, W


Book ID
110053889
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
75 KB
Volume
12
Category
Article
ISSN
0887-6924

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Effective treatment of the elderly patients (265 years) with acute nonlymphocytic leukemia (ANLL) remains elusive and controversial. In the present study, single-agent Cytosine Arabinoside (AM-C) was administered at an intermediate dose level (500 mg/m2 intravenously [I.V.] I-hour infusion q12 hours