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High-dose VP-16 with intermediate-dose cytosine arabinoside in the treatment of relapsed acute nonlymphocytic leukemia

✍ Scribed by Hon Y. Chan; Frederick J. Meyers; Jerry P. Lewis


Publisher
Springer
Year
1987
Tongue
English
Weight
147 KB
Volume
20
Category
Article
ISSN
0344-5704

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Treatment of acute nonlymphocytic leukem
✍ Letendre, Louis ;Niedringhaus, Robert D. ;Therneau, Terry M. ;Gastineau, Dennis πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 362 KB πŸ‘ 1 views

Effective treatment of the elderly patients (265 years) with acute nonlymphocytic leukemia (ANLL) remains elusive and controversial. In the present study, single-agent Cytosine Arabinoside (AM-C) was administered at an intermediate dose level (500 mg/m2 intravenously [I.V.] I-hour infusion q12 hours

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A total of 65 patients under the age of 55 with acute leukaemia received high-dose cytosine arabinoside (Ara-C) in combination with high-dose etoposide without an anthracycline. Complete remission rates for patients with relapsed or refractory acute myelogenous leukaemia (AML) were 15/25 (60%) and 1