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Limited efficacy of a four-day course of high-dose cytosine arabinoside in the treatment of poor-risk patients with acute nonlymphocytic leukemia

✍ Scribed by Harvey D. Preisler; Azra Raza; Richard Larson; George Browman; Jack Goldberg; Hans Grunwald; Ralph Vogler; John Bennett; Arlan Gottlieb; Peter D'Arrigo

Publisher
Springer
Year
1986
Tongue
English
Weight
351 KB
Volume
18
Category
Article
ISSN
0344-5704

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Treatment of acute nonlymphocytic leukem
Treatment of acute nonlymphocytic leukemia in the elderly with intermediate high-dose cytosine arabinoside
✍ Letendre, Louis ;Niedringhaus, Robert D. ;Therneau, Terry M. ;Gastineau, Dennis πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 362 KB πŸ‘ 1 views

Effective treatment of the elderly patients (265 years) with acute nonlymphocytic leukemia (ANLL) remains elusive and controversial. In the present study, single-agent Cytosine Arabinoside (AM-C) was administered at an intermediate dose level (500 mg/m2 intravenously [I.V.] I-hour infusion q12 hours

High-dose cytosine arabinoside in the tr
High-dose cytosine arabinoside in the treatment of refractory acute nonlymphocytic leukemia in adults: Results of two six-day regimens
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High-dose cytosine arabinoside (Ara-C) was used in adult patients with refractory acute nonlymphoblastic leukemia, either alone (3 g/m2 every 12 h X 12 doses) or with 3 additional days of anthracycline antibiotics. The systemic toxicities were similar for both groups without an increase in the group