The rare phenotypes PGM1, determined by alleles PGM1(3), PGM1(4), PGM1(6), and PGM1(7) were examined by starch gel electrophoresis and cellulose acetate gel isoelectric focusing and were compared with the commonest phenotypes of PGM1. The frequencies of the rare genes found in the Polish populations
Subtypes of the phosphoglucomutase-1 (PGM1) locus detectable in Polish populations by isoelectric focusing on cellogel
✍ Scribed by Tadeusz Dobosz; Piotr Kozioŀ
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 238 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
✦ Synopsis
The technique of isoelectric focusing on methylated 'cellogel' strips (CAGIF) was used to confirm the presence of four alleles of PGM1 in human red cell lysates. The subtypes of PGM1 were determined in two Polish population samples, from Southwestern Poland (Wrocław region, n=321) and Southeastern Poland (Lubin region, n=212). Ten different phenotypes are considered as gene products of four alleles at PGM1, with the following frequencies: Wrocław: PGM1F, 0.1044; PGM1S, 0.5966; PGM2F, 0.0685; and PGM2S, 0.2305; Lublin: PGM1F, 0.1439; PGM1S, 0.6014; PGM2F, 0.0825; and PGM2S, 0.1722.
📜 SIMILAR VOLUMES
The distribution of the human red cell phosphoglucomutase (PGM1) subtypes in samples from Japanese population (n--277) living in the Miyagi Prefecture, the northern part of Japan, was investigated by applying the thinlayer polyacrylamide gel isoelectric focusing. In our population sample all the ten
The existence of four alleles of phosphoglucomutase (PGM1) in human red cell lysates has previously been demonstrated by isoelectric focusing (Bark et al., 1976; Kühnl et al., 1977; Sutton and Burgess, 1978). Experiments are now described in which the position of each of the first-locus (PGM1) and s
Phosphoglucomutase1 (PGM1) polymorphism was studied in a French-Canadian population of Québec city, Canada by means of a low voltage (max 500 V) isoelectric focusing (IEF) procedure on vertical polyacrylamide gel slabs. Frequencies of the four common PGM1 genes estimated from the phenotype distribut