๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Substituent effects on the reaction of trityl chlorides with Grignard reagents

โœ Scribed by Ryan E. Oyler; Benjamin E. Ketz; Timothy E. Glass

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
77 KB
Volume
41
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

The result of the substitution of trityl chlorides with Grignard reagents was found to be highly dependent on the solvent and the nature of the substituents on the trityl group. In THF, electron donating substituents were found to give high yields of Grignard addition while electron withdrawing substituents were found to give mostly reduction to the corresponding triphenyl methane via hydride abstraction from the solvent.

๐Ÿ“œ SIMILAR VOLUMES

Functionalized ketones by iron mediated
Functionalized ketones by iron mediated reaction of grignard reagents with acyl chlorides
โœ C. Cardellicchio; V. Fiandanese; G. Marchese; L. Ronzini ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 219 KB

The iron(:II)-catalyzed cross-coupling reaction between Grignard reagents and acyl \_\_\_chlorides was found to be widely applicable to the synthesis of various functionalized ketones in good yields under mild conditions; the series of examples includes the synthesis of chiral methyl ketones and sym

Remarkable stabilizing effects of silyl
Remarkable stabilizing effects of silyl group on furfuryl chlorides and furfuryl Grignard reagents
โœ Keijiro Takanishi; Hirokazu Urabe; Isao Kuwajima ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 125 KB

Sumnary: By introducing a silyl group on their 5-position, furfuryl chlorides and the Grignard reagents have been stabilized remarkably and the Grignard reagents have exhibited unusual ambident behavior toward several electrophiles. Different from other organic halides, furfuryl chlorides are usuall