Studies on the Grignard Reaction-VI. Ste
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J. van Schoote; M. Anteunis
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Article
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2010
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Wiley (John Wiley & Sons)
β 132 KB
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## Abstract The reactivity in the normal Grignard addition reaction is greatly reduced when the ketone is branched in the Ξ±βposition. Alkylation in Ξ²βposition has only slight effect and in the Ξ³βposition there is no effect at all.